BM 2251 BIOMEDICAL INSTRUMENTATION SYLLABUS R-2008

BM 2251 BIOMEDICAL INSTRUMENTATION L T P C
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UNIT I BIO POTENTIAL ELECTRODES 9 Origin of bio potential and its propagation. Electrode-electrolyte interface, electrode–skin interface, half cell potential, impedance, polarization effects of electrode – nonpolarizable electrodes. Types of electrodes - surface, needle and micro electrodes and their equivalent circuits. Recording problems - measurement with two electrodes.

UNIT II ELECTRODE CONFIGURATIONS 9
Biosignals characteristics – frequency and amplitude ranges. ECG – Einthoven’s triangle, standard 12 lead system. EEG – 10-20 electrode system, unipolar, bipolar and average mode. EMG, ERG and EOG – unipolar and bipolar mode.

UNIT III BIO AMPLIFIER 8
Need for bio-amplifier - single ended bio-amplifier, differential bio-amplifier – right leg driven ECG amplifier. Band pass filtering, isolation amplifiers – transformer and optical isolation - isolated DC amplifier and AC carrier amplifier. Chopper amplifier. Power line interference.

UNIT IV MEASUREMENT OF NON-ELECTRICAL PARAMETER 10
Temperature, respiration rate and pulse rate measurements. Blood Pressure: indirect methods - auscultatory method, oscillometric method, direct methods: electronic manometer, Pressure amplifiers - systolic, diastolic, mean detector circuit.
Blood flow and cardiac output measurement: Indicator dilution, thermal dilution and dye dilution method, Electromagnetic and ultrasound blood flow measurement.

UNIT V BIO-CHEMICAL MEASUREMENT 9
Biochemical sensors - pH, pO2 and pCo2, Ion selective Field effect Transistor (ISFET), Immunologically sensitive FET (IMFET), Blood glucose sensors - Blood gas analyzers, colorimeter, flame photometer, spectrophotometer, blood cell counter, auto analyzer (simplified schematic description).
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TEXT BOOKS:
1. Joseph J. Carr and John M. Brown, “Introduction to Biomedical Equipment Technology”, Pearson Education, 2004.
2. John G. Webster, “Medical Instrumentation Application and Design”, John Wiley and sons, New York, 2004

REFERENCE
1. Leslie Cromwell, “Biomedical Instrumentation and measurement”, Prentice hall of India, New Delhi, 2007.
2. Khandpur R.S, “Handbook of Biomedical Instrumentation”, Tata McGraw-Hill, New Delhi, 2003.
3. Standard Handbook of Biomedical Engineering & Design – Myer Kutz, McGraw-Hill Publisher, 2003.

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